Pigment Epithelium-Derived Factor 34-mer Peptide Prevents Liver Fibrosis and Hepatic Stellate Cell Activation through Down-Regulation of the PDGF Receptor

Pigment Epithelium-Derived Factor 34-mer Peptide Prevents Liver Fibrosis and Hepatic Stellate Cell Activation through Down-Regulation of the PDGF Receptor

Pigment epithelium-derived factor (PEDF) has been shown previously to prevent liver fibrosis and hepatic stellate cell (HSC) activation. By investigating the functional domains in PEDF, we identified a 34-mer peptide (residues Asp44-Asn77) that harbors the same function as the full-length PEDF prote...

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Bibliographic Details
Main Authors: Tsai, Tung-Han, Shih, Shou-Chuan, Ho, Tsung-Chuan, Ma, Hsin-I, Liu, Ming-Ying, Chen, Show-Li, Tsao, Yeou-Ping
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998957/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998957/

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