TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers

Immune responses at mucosal barriers are regulated by innate type 2 lymphoid cells (ILC2s) that elaborate effector cytokines interleukins 5 and 13 (IL5 and IL13). IL25 and IL33 are key cytokines that support ILC2s; however, mice deficient in these pathways retain some functional ILC2s. Analysis of h...

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Bibliographic Details
Main Authors: Yu, X, Pappu, R, Ramirez-Carrozzi, V, Ota, N, Caplazi, P, Zhang, J, Yan, D, Xu, M, Lee, W P, Grogan, J L
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998636/