Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients

Flagellated protozoa that cause bronchopulmonary symptoms in humans are commonly neglected. These protozoal forms which were presumed to be “flagellated protozoa” have been previously identified in immunosuppressed patients in a number of studies, but have not been certainly classified so far. Since...

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Main Authors:	Kilimcioglu, Ali Ahmet, Havlucu, Yavuz, Girginkardesler, Nogay, Çelik, Pınar, Yereli, Kor, Özbilgin, Ahmet
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996290/

id	pubmed-3996290
recordtype	oai_dc
spelling	pubmed-39962902014-05-06 Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients Kilimcioglu, Ali Ahmet Havlucu, Yavuz Girginkardesler, Nogay Çelik, Pınar Yereli, Kor Özbilgin, Ahmet Research Article Flagellated protozoa that cause bronchopulmonary symptoms in humans are commonly neglected. These protozoal forms which were presumed to be “flagellated protozoa” have been previously identified in immunosuppressed patients in a number of studies, but have not been certainly classified so far. Since no human cases of bronchopulmonary flagellated protozoa were reported from Turkey, we aimed to investigate these putative protozoa in immunosuppressed patients who are particularly at risk of infectious diseases. Bronchoalveolar lavage fluid samples of 110 immunosuppressed adult patients who were admitted to the Department of Chest Diseases, Hafsa Sultan Hospital of Celal Bayar University, Manisa, Turkey, were examined in terms of parasites by light microscopy. Flagellated protozoal forms were detected in nine (8.2%) of 110 cases. Metronidazole (500 mg b.i.d. for 30 days) was given to all positive cases and a second bronchoscopy was performed at the end of the treatment, which revealed no parasites. In conclusion, immunosuppressed patients with bronchopulmonary symptoms should attentively be examined with regard to flagellated protozoa which can easily be misidentified as epithelial cells. Hindawi Publishing Corporation 2014 2014-04-03 /pmc/articles/PMC3996290/ /pubmed/24804259 http://dx.doi.org/10.1155/2014/912346 Text en Copyright © 2014 Ali Ahmet Kilimcioglu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Kilimcioglu, Ali Ahmet Havlucu, Yavuz Girginkardesler, Nogay Çelik, Pınar Yereli, Kor Özbilgin, Ahmet
spellingShingle	Kilimcioglu, Ali Ahmet Havlucu, Yavuz Girginkardesler, Nogay Çelik, Pınar Yereli, Kor Özbilgin, Ahmet Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
author_facet	Kilimcioglu, Ali Ahmet Havlucu, Yavuz Girginkardesler, Nogay Çelik, Pınar Yereli, Kor Özbilgin, Ahmet
author_sort	Kilimcioglu, Ali Ahmet
title	Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_short	Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_full	Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_fullStr	Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_full_unstemmed	Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_sort	putative bronchopulmonary flagellated protozoa in immunosuppressed patients
description	Flagellated protozoa that cause bronchopulmonary symptoms in humans are commonly neglected. These protozoal forms which were presumed to be “flagellated protozoa” have been previously identified in immunosuppressed patients in a number of studies, but have not been certainly classified so far. Since no human cases of bronchopulmonary flagellated protozoa were reported from Turkey, we aimed to investigate these putative protozoa in immunosuppressed patients who are particularly at risk of infectious diseases. Bronchoalveolar lavage fluid samples of 110 immunosuppressed adult patients who were admitted to the Department of Chest Diseases, Hafsa Sultan Hospital of Celal Bayar University, Manisa, Turkey, were examined in terms of parasites by light microscopy. Flagellated protozoal forms were detected in nine (8.2%) of 110 cases. Metronidazole (500 mg b.i.d. for 30 days) was given to all positive cases and a second bronchoscopy was performed at the end of the treatment, which revealed no parasites. In conclusion, immunosuppressed patients with bronchopulmonary symptoms should attentively be examined with regard to flagellated protozoa which can easily be misidentified as epithelial cells.
publisher	Hindawi Publishing Corporation
publishDate	2014
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996290/
_version_	1612081193917874176

Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients

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