Retrotransposition in tumors and brains
LINE-1s (L1s), the only currently active autonomous mobile DNA in humans, occupy at least 17% of human DNA. Throughout evolution, the L1 has also been responsible for genomic insertion of thousands of processed pseudogenes and over one million nonautonomous retrotransposons called SINEs (mainly Alus...
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Format: | Online |
Language: | English |
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BioMed Central
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995500/ |