JC Virus Inclusions in Progressive Multifocal Leukoencephalopathy: Scaffolding Promyelocytic Leukemia Nuclear Bodies Grow With Cell Cycle Transition Through an S-to-G2–Like State in Enlarging Oligodendrocyte Nuclei

JC Virus Inclusions in Progressive Multifocal Leukoencephalopathy: Scaffolding Promyelocytic Leukemia Nuclear Bodies Grow With Cell Cycle Transition Through an S-to-G2–Like State in Enlarging Oligodendrocyte Nuclei

In progressive multifocal leukoencephalopathy, JC virus–infected oligodendroglia display 2 distinct patterns of intranuclear viral inclusions: full inclusions in which progeny virions are present throughout enlarged nuclei and dot-shaped inclusions in which virions are clustered in subnuclear domain...

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Bibliographic Details
Main Authors: Shishido-Hara, Yukiko, Yazawa, Takuya, Nagane, Motoo, Higuchi, Kayoko, Abe-Suzuki, Shiho, Kurata, Morito, Kitagawa, Masanobu, Kamma, Hiroshi, Uchihara, Toshiki
Format: Online
Language:English
Published: American Association of Neuropathologists 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995394/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995394/

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