Kir3 channel ontogeny – the role of Gβγ subunits in channel assembly and trafficking

The role of Gβγ subunits in Kir3 channel gating is well characterized. Here, we have studied the role of Gβγ dimers during their initial contact with Kir3 channels, prior to their insertion into the plasma membrane. We show that distinct Gβγ subunits play an important role in orchestrating and fine-...

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Bibliographic Details
Main Authors: Zylbergold, Peter, Sleno, Rory, Khan, Shahriar M., Jacobi, Ashley M., Belhke, Mark A., Hébert, Terence E.
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995069/