FOXP2
The forkhead box P2 gene, designated FOXP2, is the first gene implicated in a speech and language disorder. Since its discovery, many studies have been carried out in an attempt to explain the mechanism by which it influences these characteristically human traits. This review presents the story of t...
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| Format: | Online |
| Language: | English |
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John Wiley & Sons, Inc.
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992897/ |
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pubmed-3992897 |
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pubmed-39928972014-04-22 FOXP2 Nudel, Ron Newbury, Dianne F Advanced Review The forkhead box P2 gene, designated FOXP2, is the first gene implicated in a speech and language disorder. Since its discovery, many studies have been carried out in an attempt to explain the mechanism by which it influences these characteristically human traits. This review presents the story of the discovery of the FOXP2 gene, including early studies of the phenotypic implications of a disruption in the gene. We then discuss recent investigations into the molecular function of the FOXP2 gene, including functional and gene expression studies. We conclude this review by presenting the fascinating results of recent studies of the FOXP2 ortholog in other species that are capable of vocal communication. WIREs Cogn Sci 2013, 4:547–560. doi: 10.1002/wcs.1247 John Wiley & Sons, Inc. 2013-09 2013-08-13 /pmc/articles/PMC3992897/ /pubmed/24765219 http://dx.doi.org/10.1002/wcs.1247 Text en © 2013 The Authors. WIREs Cognitive Science published by John Wiley & Sons, Ltd. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Nudel, Ron Newbury, Dianne F |
| spellingShingle |
Nudel, Ron Newbury, Dianne F FOXP2 |
| author_facet |
Nudel, Ron Newbury, Dianne F |
| author_sort |
Nudel, Ron |
| title |
FOXP2 |
| title_short |
FOXP2 |
| title_full |
FOXP2 |
| title_fullStr |
FOXP2 |
| title_full_unstemmed |
FOXP2 |
| title_sort |
foxp2 |
| description |
The forkhead box P2 gene, designated FOXP2, is the first gene implicated in a speech and language disorder. Since its discovery, many studies have been carried out in an attempt to explain the mechanism by which it influences these characteristically human traits. This review presents the story of the discovery of the FOXP2 gene, including early studies of the phenotypic implications of a disruption in the gene. We then discuss recent investigations into the molecular function of the FOXP2 gene, including functional and gene expression studies. We conclude this review by presenting the fascinating results of recent studies of the FOXP2 ortholog in other species that are capable of vocal communication. WIREs Cogn Sci 2013, 4:547–560. doi: 10.1002/wcs.1247 |
| publisher |
John Wiley & Sons, Inc. |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992897/ |
| _version_ |
1612080172916277248 |