Striatal dysfunction during reversal learning in unmedicated schizophrenia patients☆

Subjects with schizophrenia are impaired at reinforcement-driven reversal learning from as early as their first episode. The neurobiological basis of this deficit is unknown. We obtained behavioral and fMRI data in 24 unmedicated, primarily first episode, schizophrenia patients and 24 age-, IQ- and...

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Bibliographic Details
Main Authors: Schlagenhauf, Florian, Huys, Quentin J.M., Deserno, Lorenz, Rapp, Michael A., Beck, Anne, Heinze, Hans-Joachim, Dolan, Ray, Heinz, Andreas
Format: Online
Language:English
Published: Academic Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991847/