Local translation of TC10 is required for membrane expansion during axon outgrowth

The surface of developing axons expands in a process mediated by the exocyst complex. The spatial-temporal regulation of the exocyst is only partially understood. Here we report that stimulated membrane enlargement in dorsal root ganglion (DRG) axons is triggered by intra-axonal synthesis of TC10, a...

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Bibliographic Details
Main Authors: Gracias, Neilia G., Shirkey-Son, Nicole J., Hengst, Ulrich
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991842/