Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum

Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite utilized as a redox cofactor and enzyme substrate in numerous cellular processes. Elevated NAD+ levels have been observed in red blood cells infected with the malaria parasite Plasmodium falciparum, but little is known regarding how...

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Bibliographic Details
Main Authors: O'Hara, Jessica K., Kerwin, Lewis J., Cobbold, Simon A., Tai, Jonathan, Bedell, Thomas A., Reider, Paul J., Llinás, Manuel
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991606/