Pien Tze Huang inhibits hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells through suppression of the HIF-1 pathway

Hypoxia-induced activation of the hypoxia-inducible factor 1 (HIF-1) signaling pathway is frequently observed in solid tumors and is strongly associated with numerous pathophysiological processes, including the induction of epithelial-mesenchymal transition (EMT), which result in cancer progression...

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Bibliographic Details
Main Authors: CHEN, HONGWEI, SHEN, ALING, ZHANG, YUCHEN, CHEN, YOUQIN, LIN, JIUMAO, LIN, WEI, SFERRA, THOMAS, PENG, JUN
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991510/