Effects of Hypocretin/Orexin Cell Transplantation on Narcoleptic-Like Sleep Behavior in Rats

The sleep disorder narcolepsy is now considered a neurodegenerative disease because there is a massive loss of neurons containing the neuropeptide hypocretin/orexin (HCRT). In consequence, narcoleptic patients have very low cerebrospinal fluid (CSF) levels of HCRT. Studies in animal models of narcol...

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Bibliographic Details
Main Authors: Arias-Carrión, Oscar, Murillo-Rodríguez, Eric
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988205/