New insights into an X-traordinary viral protein
Vpx is a protein encoded by members of the HIV-2/SIVsmm and SIVrcm/SIVmnd-2 lineages of primate lentiviruses, and is packaged into viral particles. Vpx plays a critical role during the early steps of the viral life cycle and has been shown to counteract SAMHD1, a restriction factor in myeloid and re...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986551/ |