Heterogeneous Intracellular Trafficking Dynamics of Brain-Derived Neurotrophic Factor Complexes in the Neuronal Soma Revealed by Single Quantum Dot Tracking

Accumulating evidence underscores the importance of ligand-receptor dynamics in shaping cellular signaling. In the nervous system, growth factor-activated Trk receptor trafficking serves to convey biochemical signaling that underlies fundamental neural functions. Focus has been placed on axonal traf...

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Bibliographic Details
Main Authors: Vermehren-Schmaedick, Anke, Krueger, Wesley, Jacob, Thomas, Ramunno-Johnson, Damien, Balkowiec, Agnieszka, Lidke, Keith A., Vu, Tania Q.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986401/