Synthesis of Brominated 2-Phenitidine Derivatives as Valuable Inhibitors of Cholinesterases for the Treatment of Alzheimer’s Disease
The present study reports the synthesis of a series N-substituted derivatives of brominated 2-phenitidine. First, the reaction of 2-phenitidine (1) with benzenesulfonyl chloride (2) in aqueous media yielded N-(2-ethoxyphenyl) benzenesulfonamide (3), which was then subjected to bromination with bromi...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Shaheed Beheshti University of Medical Sciences
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985256/ |