p150glued-Associated Disorders Are Caused by Activation of Intrinsic Apoptotic Pathway

p150glued-Associated Disorders Are Caused by Activation of Intrinsic Apoptotic Pathway

Mutations in p150glued cause hereditary motor neuropathy with vocal cord paralysis (HMN7B) and Perry syndrome (PS). Here we show that both overexpression of p150glued mutants and knockdown of endogenous p150glued induce apoptosis. Overexpression of a p150glued plasmid containing either a HMN7B or PS...

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Bibliographic Details
Main Authors: Ishikawa, Kei-Ichi, Saiki, Shinji, Furuya, Norihiko, Yamada, Daisuke, Imamichi, Yoko, Li, Yuanzhe, Kawajiri, Sumihiro, Sasaki, Hironori, Koike, Masato, Tsuboi, Yoshio, Hattori, Nobutaka
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983229/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983229/

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