Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii

Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii

During infection with the intracellular parasite Toxoplasma gondii, the presentation of parasite-derived antigens to CD4+ and CD8+ T cells is essential for long-term resistance to this pathogen. Fundamental questions remain regarding the roles of phagocytosis and active invasion in the events that l...

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Bibliographic Details
Main Authors: Dupont, Christopher D., Christian, David A., Selleck, Elizabeth M., Pepper, Marion, Leney-Greene, Michael, Harms Pritchard, Gretchen, Koshy, Anita A., Wagage, Sagie, Reuter, Morgan A., Sibley, L. David, Betts, Michael R., Hunter, Christopher A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983043/

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