Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex trait/disease and the genetic correlation between two complex traits/diseases using genome-wide single nucleotide polymorphism (SNP) data in unrelated individuals. Here we use analytical derivations and...

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Bibliographic Details
Main Authors: Visscher, Peter M., Hemani, Gibran, Vinkhuyzen, Anna A. E., Chen, Guo-Bo, Lee, Sang Hong, Wray, Naomi R., Goddard, Michael E., Yang, Jian
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983037/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983037/

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