Cobblestone-Area Forming Cells Derived from Patients with Mantle Cell Lymphoma Are Enriched for CD133+ Tumor-Initiating Cells

Mantle cell lymphoma (MCL) is associated with a significant risk of therapeutic failure and disease relapse, but the biological origin of relapse is poorly understood. Here, we prospectively identify subpopulations of primary MCL cells with different biologic and immunophenotypic features. Using a s...

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Bibliographic Details
Main Authors: Medina, Daniel J., Abass-Shereef, Jeneba, Walton, Kelly, Goodell, Lauri, Aviv, Hana, Strair, Roger K., Budak-Alpdogan, Tulin
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982953/