Age and SPARC Change the Extracellular Matrix Composition of the Left Ventricle

Secreted protein acidic and rich in cysteine (SPARC), a collagen-binding matricellular protein, has been implicated in procollagen processing and deposition. The aim of this study was to investigate age- and SPARC-dependent changes in protein composition of the cardiac extracellular matrix (ECM). We...

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Bibliographic Details
Main Authors: de Castro Brás, Lisandra E., Toba, Hiroe, Baicu, Catalin F., Zile, Michael R., Weintraub, Susan T., Lindsey, Merry L., Bradshaw, Amy D.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982264/