Translational Signalling, Atrogenic and Myogenic Gene Expression during Unloading and Reloading of Skeletal Muscle in Myostatin-Deficient Mice

Translational Signalling, Atrogenic and Myogenic Gene Expression during Unloading and Reloading of Skeletal Muscle in Myostatin-Deficient Mice

Skeletal muscles of myostatin null (Mstn(−/−)) mice are more susceptible to atrophy during hind limb suspension (HS) than are muscles of wild-type mice. Here we sought to elucidate the mechanism for this susceptibility and to determine if Mstn(−/−) mice can regain muscle mass after HS. Male Mstn(−/−...

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Bibliographic Details
Main Authors: Smith, Heather K., Matthews, Kenneth G., Oldham, Jenny M., Jeanplong, Ferenc, Falconer, Shelley J., Bass, James J., Senna-Salerno, Mônica, Bracegirdle, Jeremy W., McMahon, Christopher D.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981781/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981781/

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