Activated Scavenger Receptor A Promotes Glial Internalization of Aβ

Beta-amyloid (Aβ) aggregates have a pivotal role in pathological processing of Alzheimer’s disease (AD). The clearance of Aβ monomer or aggregates is a causal strategy for AD treatment. Microglia and astrocytes are the main macrophages that exert critical neuroprotective roles in the brain. They may...

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Bibliographic Details
Main Authors: Zhang, He, Su, Ya-jing, Zhou, Wei-wei, Wang, Shao-wei, Xu, Peng-xin, Yu, Xiao-lin, Liu, Rui-tian
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981768/