Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications
Multiple subclonal populations of tumor cells can coexist within the same tumor. This intra-tumor heterogeneity will have clinical implications and it is therefore important to identify factors that drive or suppress such heterogeneous tumor progression. Evolutionary biology can provide important in...
Main Authors: | de Bruin, Elza C, Taylor, Tiffany B, Swanton, Charles |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978608/ |
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