A simple consensus approach improves somatic mutation prediction accuracy

Differentiating true somatic mutations from artifacts in massively parallel sequencing data is an immense challenge. To develop methods for optimal somatic mutation detection and to identify factors influencing somatic mutation prediction accuracy, we validated predictions from three somatic mutatio...

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Bibliographic Details
Main Authors: Goode, David L, Hunter, Sally M, Doyle, Maria A, Ma, Tao, Rowley, Simone M, Choong, David, Ryland, Georgina L, Campbell, Ian G
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978449/