CD80 and CD86 Costimulatory Molecules Differentially Regulate OT-II CD4+ T Lymphocyte Proliferation and Cytokine Response in Cocultures with Antigen-Presenting Cells Derived from Pregnant and Pseudopregnant Mice
Immune phenomena during the preimplantation period of pregnancy are poorly understood. The aim of our study was to assess the capacity for antigen presentation of splenic antigen-presenting cells (APCs) derived from pregnant and pseudopregnant mice in in vitro conditions. Therefore, sorted CD11c+ de...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977523/ |