Polyamine blockade promotes antitumor immunity
The levels of polyamines are elevated in neoplastic lesions as compared with normal tissues, and cancer cells tend to manifest a robust dependence on these compounds for proliferation and survival. We have recently demonstrated that a novel approach to polyamine depletion suppresses tumor growth in...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Landes Bioscience
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976981/ |