TGF-β Signaling Regulates Neuronal C1q Expression and Developmental Synaptic Refinement

Immune molecules, including complement proteins C1q and C3, have emerged as critical mediators of synaptic refinement and plasticity. Complement localizes to synapses and refines the developing visual system via C3-dependent microglial phagocytosis of synapses. Retinal ganglion cells (RGCs) express...

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Bibliographic Details
Main Authors: Bialas, Allison R., Stevens, Beth
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973738/