Simultaneous reconstruction of evolutionary history and epidemiological dynamics from viral sequences with the birth–death SIR model
The evolution of RNA viruses, such as human immunodeficiency virus (HIV), hepatitis C virus and influenza virus, occurs so rapidly that the viruses' genomes contain information on past ecological dynamics. Hence, we develop a phylodynamic method that enables the joint estimation of epidemiologi...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Royal Society
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973358/ |