Simultaneous reconstruction of evolutionary history and epidemiological dynamics from viral sequences with the birth–death SIR model

The evolution of RNA viruses, such as human immunodeficiency virus (HIV), hepatitis C virus and influenza virus, occurs so rapidly that the viruses' genomes contain information on past ecological dynamics. Hence, we develop a phylodynamic method that enables the joint estimation of epidemiologi...

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Bibliographic Details
Main Authors: Kühnert, Denise, Stadler, Tanja, Vaughan, Timothy G., Drummond, Alexei J.
Format: Online
Language:English
Published: The Royal Society 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973358/