Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae

Klebsiella pneumoniae PmrA is a polymyxin-resistance-associated response regulator. The C-terminal effector/DNA-binding domain of PmrA (PmrAC) recognizes tandem imperfect repeat sequences on the promoters of genes to induce antimicrobial peptide resistance after phosphorylation and dimerization of i...

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Bibliographic Details
Main Authors: Lou, Yuan-Chao, Wang, Iren, Rajasekaran, M., Kao, Yi-Fen, Ho, Meng-Ru, Hsu, Shang-Te Danny, Chou, Shan-Ho, Wu, Shih-Hsiung, Chen, Chinpan
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973317/