SAPTA: a new design tool for improving TALE nuclease activity

SAPTA: a new design tool for improving TALE nuclease activity

Transcription activator-like effector nucleases (TALENs) have become a powerful tool for genome editing due to the simple code linking the amino acid sequences of their DNA-binding domains to TALEN nucleotide targets. While the initial TALEN-design guidelines are very useful, user-friendly tools def...

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Bibliographic Details
Main Authors: Lin, Yanni, Fine, Eli J., Zheng, Zhilan, Antico, Christopher J., Voit, Richard A., Porteus, Matthew H., Cradick, Thomas J., Bao, Gang
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973288/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973288/

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