D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation

Non-enzymatic glycation of proteins by reducing saccharides for instance D-glucose is an important post-translational modification regulating protein function. Already two centuries ago, D-glucose (Glc) was identified in the urine of diabetic patients. Recently, abnormally high level of D-ribose (Ri...

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Bibliographic Details
Main Authors: Han, C, Lu, Y, Wei, Y, Wu, B, Liu, Y, He, R
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973213/