URI regulates tumorigenicity and chemotherapeutic resistance of multiple myeloma by modulating IL-6 transcription

URI regulates tumorigenicity and chemotherapeutic resistance of multiple myeloma by modulating IL-6 transcription

Unconventional prefoldin RPB5 interactor (URI), which acts as an oncoprotein in solid tumors, is associated with RNA polymerase II subunit 5. However, its impact on multiple myeloma (MM) has not been determined. We demonstrate here that URI is overexpressed in MM compared with plasma cells derived f...

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Bibliographic Details
Main Authors: Fan, J-L, Zhang, J, Dong, L-W, Fu, W-J, Du, J, Shi, H-G, Jiang, H, Ye, F, Xi, H, Zhang, C-Y, Hou, J, Wang, H-Y
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973192/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973192/

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