Morphological Features of Organelles during Apoptosis: An Overview

An apoptotic program leading to controlled cell dismantling implies perturbations of nuclear dynamics, as well as changes affecting the organelle structure and distribution. In human cancer cells driven to apoptosis by different stimuli, we have recently investigated the morphological properties of...

Full description

Bibliographic Details
Main Authors:	Bottone, Maria Grazia, Santin, Giada, Aredia, Francesca, Bernocchi, Graziella, Pellicciari, Carlo, Scovassi, Anna Ivana
Format:	Online
Language:	English
Published:	MDPI 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972681/

id	pubmed-3972681
recordtype	oai_dc
spelling	pubmed-39726812014-04-07 Morphological Features of Organelles during Apoptosis: An Overview Bottone, Maria Grazia Santin, Giada Aredia, Francesca Bernocchi, Graziella Pellicciari, Carlo Scovassi, Anna Ivana Review An apoptotic program leading to controlled cell dismantling implies perturbations of nuclear dynamics, as well as changes affecting the organelle structure and distribution. In human cancer cells driven to apoptosis by different stimuli, we have recently investigated the morphological properties of several organelles, including mitochondria, lysosomes, endoplasmic reticulum and Golgi apparatus. In this review, we will discuss the body of evidence in the literature suggesting that organelles are generally relocated and/or degraded during apoptosis, irrespectively of the apoptogenic stimulus and cell type. MDPI 2013-05-07 /pmc/articles/PMC3972681/ /pubmed/24709702 http://dx.doi.org/10.3390/cells2020294 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Bottone, Maria Grazia Santin, Giada Aredia, Francesca Bernocchi, Graziella Pellicciari, Carlo Scovassi, Anna Ivana
spellingShingle	Bottone, Maria Grazia Santin, Giada Aredia, Francesca Bernocchi, Graziella Pellicciari, Carlo Scovassi, Anna Ivana Morphological Features of Organelles during Apoptosis: An Overview
author_facet	Bottone, Maria Grazia Santin, Giada Aredia, Francesca Bernocchi, Graziella Pellicciari, Carlo Scovassi, Anna Ivana
author_sort	Bottone, Maria Grazia
title	Morphological Features of Organelles during Apoptosis: An Overview
title_short	Morphological Features of Organelles during Apoptosis: An Overview
title_full	Morphological Features of Organelles during Apoptosis: An Overview
title_fullStr	Morphological Features of Organelles during Apoptosis: An Overview
title_full_unstemmed	Morphological Features of Organelles during Apoptosis: An Overview
title_sort	morphological features of organelles during apoptosis: an overview
description	An apoptotic program leading to controlled cell dismantling implies perturbations of nuclear dynamics, as well as changes affecting the organelle structure and distribution. In human cancer cells driven to apoptosis by different stimuli, we have recently investigated the morphological properties of several organelles, including mitochondria, lysosomes, endoplasmic reticulum and Golgi apparatus. In this review, we will discuss the body of evidence in the literature suggesting that organelles are generally relocated and/or degraded during apoptosis, irrespectively of the apoptogenic stimulus and cell type.
publisher	MDPI
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972681/
_version_	1612073170058084352

Morphological Features of Organelles during Apoptosis: An Overview

Similar Items