Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system

Functionally and spatially distinct PI 3-K pathways act either early to promote myelination downstream of axonal Neuregulin1 or late to inhibit myelination downstream of α6β4 integrin and Sgk1.

Bibliographic Details
Main Authors: Heller, Bradley A., Ghidinelli, Monica, Voelkl, Jakob, Einheber, Steven, Smith, Ryan, Grund, Ethan, Morahan, Grant, Chandler, David, Kalaydjieva, Luba, Giancotti, Filippo, King, Rosalind H., Fejes-Toth, Aniko Naray, Fejes-Toth, Gerard, Feltri, Maria Laura, Lang, Florian, Salzer, James L.
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971744/