A directed approach for the identification of transcripts harbouring the spliced leader sequence and the effect of trans-splicing knockdown in Schistosoma mansoni

Schistosomiasis is a major neglected tropical disease caused by trematodes from the genus Schistosoma. Because schistosomes exhibit a complex life cycle and numerous mechanisms for regulating gene expression, it is believed that spliced leader (SL) trans-splicing could play an important role in the...

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Bibliographic Details
Main Authors: Mourão, Marina de Moraes, Bitar, Mainá, Lobo, Francisco Pereira, Peconick, Ana Paula, Grynberg, Priscila, Prosdocimi, Francisco, Waisberg, Michael, Cerqueira, Gustavo Coutinho, Macedo, Andréa Mara, Machado, Carlos Renato, Yoshino, Timothy, Franco, Glória Regina
Format: Online
Language:English
Published: Instituto Oswaldo Cruz 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970683/