TiO2 nanoparticles and bulk material stimulate human peripheral blood mononuclear cells☆

•Effects on immunobiochemical pathways of TiO2 materials were investigated in vitro.•TiO2 bulk and nanomaterial stimulated neopterin production in human PBMC.•There was no stimulatory influence of particles on tryptophan breakdown.•At high particles concentrations, tryptophan breakdown was suppresse...

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Bibliographic Details
Main Authors: Becker, Kathrin, Schroecksnadel, Sebastian, Geisler, Simon, Carriere, Marie, Gostner, Johanna M., Schennach, Harald, Herlin, Nathalie, Fuchs, Dietmar
Format: Online
Language:English
Published: Elsevier Science Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969306/