Plakophilins, desmogleins, and pemphigus: the tail wagging the dog

The importance of desmosomal cell adhesion to human health is evidenced by the autoimmune disease pemphigus vulgaris (PV), in which autoantibodies against the extracellular domain of the desmosomal cadherin desmoglein 3 cause potentially fatal blistering of the skin and mucous membranes. Tucker et a...

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Bibliographic Details
Main Authors: Ellebrecht, Christoph T., Payne, Aimee S.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968779/