Mutations in MAPT give rise to aneuploidy in animal models of tauopathy
Tau is a major microtubule-associated protein in brain neurons. Its misfolding and accumulation cause neurodegenerative diseases characterized by brain atrophy and dementia, named tauopathies. Genetic forms are caused by mutations of microtubule-associated protein tau gene (MAPT). Tau is expressed a...
| Main Authors: | , , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer Berlin Heidelberg
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968519/ |