The PNPLA3 Ile148Met interacts with overweight and dietary intakes on fasting triglyceride levels
The Ile148Met (rs738409, G-allele) in the patatin-like phospholipase domain-containing protein 3 gene (PNPLA3) associates with liver fat content and may lead to loss-of-function (hydrolysis) or gain-of-function (CoA-dependent lysophosphatidic acid acyltransferase) defects. PNPLA3 is up-regulated by...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer Berlin Heidelberg
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968290/ |