In vivo conversion of astrocytes to neurons in the injured adult spinal cord

In vivo conversion of astrocytes to neurons in the injured adult spinal cord

Spinal cord injury (SCI) leads to irreversible neuronal loss and glial scar formation, which ultimately result in persistent neurological dysfunction. Cellular regeneration could be an ideal approach to replenish the lost cells and repair the damage. However, the adult spinal cord has limited abilit...

Full description

Bibliographic Details
Main Authors:	Su, Zhida, Niu, Wenze, Liu, Meng-Lu, Zou, Yuhua, Zhang, Chun-Li
Format:	Online
Language:	English
Published:	2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966078/

Similar Items

The fate of proliferating cells in the injured adult spinal cord
by: McTigue, Dana M, et al.
Published: (2011)

Tracheostomy in Spinal Cord Injured Patients
by: Ganuza, Javier-Romero, et al.
Published: (2011)

SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain
by: Niu, Wenze, et al.
Published: (2015)

Bridging the injured spinal cord with neural stem cells
by: Dulin, Jennifer N., et al.
Published: (2014)

High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord
by: Beaudet, Marie-Josée, et al.
Published: (2015)

Spinal Plasticity and Behavior: BDNF-Induced Neuromodulation in Uninjured and Injured Spinal Cord
by: Garraway, Sandra M., et al.
Published: (2016)

Spinal cord injury induces astroglial conversion towards neuronal lineage
by: Noristani, Harun Najib, et al.
Published: (2016)

Building bridges with astrocytes for spinal cord repair
by: Miller, Robert H
Published: (2006)

HDAC6 Regulates the Chaperone-Mediated Autophagy to Prevent Oxidative Damage in Injured Neurons after Experimental Spinal Cord Injury
by: Su, Min, et al.
Published: (2016)

Direct conversion of astrocytes into neuronal cells by drug cocktail
by: Cheng, Lin, et al.
Published: (2015)

Organotypic Spinal Cord Slice Culture to Study Neural Stem/Progenitor Cell Microenvironment in the Injured Spinal Cord
by: Kim, Hyuk Min, et al.
Published: (2010)

Plasticity of the Injured Human Spinal Cord: Insights Revealed by Spinal Cord Functional MRI
by: Cadotte, David W., et al.
Published: (2012)

The quality of life among spinal cord injured population: Does it improve with time?
by: Radzli, RM, et al.
Published: (2011)

Reconstruction of injured spinal cord by epigenetic regulation of transplanted neural stem cells
by: Abematsu, Masahiko, et al.
Published: (2012)

Time-related effects of general functional training in spinal cord-injured rats
by: Miranda, Taisa Amoroso Bortolato, et al.
Published: (2012)

Updated evidence-based screening and treatment of osteoporosis in spinal cord injured patients
by: Maheronnaghsh, Radin, et al.
Published: (2012)

Abundant Expression of Guidance and Synaptogenic Molecules in the Injured Spinal Cord
by: Jacobi, Anne, et al.
Published: (2014)

Efficacy of a Metalloproteinase Inhibitor in Spinal Cord Injured Dogs
by: Levine, Jonathan M., et al.
Published: (2014)

Endogenous neural progenitor cells in the repair of the injured spinal cord
by: Mao, Yilin, et al.
Published: (2016)

Bridging large gaps in the injured spinal cord: mechanical and biochemical tissue adaptation
by: Estrada, Veronica, et al.
Published: (2016)

The effect of increased ambient temperature on thermoregulatory responses in spinal cord injured people
by: Yoda, Tamae, et al.
Published: (2015)

Leuprolide acetate induces structural and functional recovery of injured spinal cord in rats
by: Díaz Galindo, Carmen, et al.
Published: (2015)

Guiding migration of transplanted glial progenitor cells in the injured spinal cord
by: Yuan, Xiao-bing, et al.
Published: (2016)

X-irradiation for inhibiting glial scar formation in injured spinal cord☆
by: Ning, Guangzhi, et al.
Published: (2013)

Repair of injured spinal cord using biomaterial scaffolds and stem cells
by: Shrestha, Bikesh, et al.
Published: (2014)

Gastrodin promotes the secretion of brain-derived neurotrophic factor in the injured spinal cord
by: Song, Changwei, et al.
Published: (2013)

Repairing the injured spinal cord: sprouting versus regeneration. Is this a realistic match?
by: Fouad, Karim, et al.
Published: (2014)

Transplantation of choroid plexus epithelial cells into contusion-injured spinal cord of rats
by: Kanekiyo, Kenji, et al.
Published: (2016)

Management of febrile urinary tract infection among spinal cord injured patients
by: Dinh, Aurélien, et al.
Published: (2016)

Effects of Dibutyryl Cyclic-AMP on Survival and Neuronal Differentiation of Neural Stem/Progenitor Cells Transplanted into Spinal Cord Injured Rats
by: Kim, Howard, et al.
Published: (2011)

Electroacupuncture promotes the recovery of motor neuron function in the anterior horn of the injured spinal cord
by: Yang, Jian-hui, et al.
Published: (2015)

Transplanting neural progenitors to build a neuronal relay across the injured spinal cord
by: Haas, Christopher, et al.
Published: (2014)

In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord
by: Morsch, Marco, et al.
Published: (2015)

Prediction of gait recovery in spinal cord injured individuals trained with robotic gait orthosis
by: Niu, Xun, et al.
Published: (2014)

Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats☆
by: Wu, Haiying, et al.
Published: (2012)

Sox2-Mediated Conversion of NG2 Glia into Induced Neurons in the Injured Adult Cerebral Cortex
by: Heinrich, Christophe, et al.
Published: (2014)

Spatial and temporal correlation in progressive degeneration of neurons and astrocytes in contusion-induced spinal cord injury
by: Min, Kyoung-Jin, et al.
Published: (2012)

The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons
by: Ehmsen, Jeffrey T., et al.
Published: (2016)

The Modulation of Neurotrophin and Epigenetic Regulators: Implication for Astrocyte Proliferation and Neuronal Cell Apoptosis After Spinal Cord Injury
by: Kim, Jong Heon, et al.
Published: (2016)

Astrocytes derived from glial-restricted precursors promote spinal cord repair
by: Davies, Jeannette E, et al.
Published: (2006)