Cyclodextrin and Polyethylenimine Functionalized Mesoporous Silica Nanoparticles for Delivery of siRNA Cancer Therapeutics

Cyclodextrin and Polyethylenimine Functionalized Mesoporous Silica Nanoparticles for Delivery of siRNA Cancer Therapeutics

Effective delivery holds the key to successful in vivo application of therapeutic small interfering RNA (siRNA). In this work, we have developed a universal siRNA carrier consisting of a mesoporous silica nanoparticle (MSNP) functionalized with cyclodextrin-grafted polyethylenimine (CP). CP provides...

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Bibliographic Details
Main Authors: Shen, Jianliang, Kim, Han-Cheon, Su, Hua, Wang, Feng, Wolfram, Joy, Kirui, Dickson, Mai, Junhua, Mu, Chaofeng, Ji, Liang-Nian, Mao, Zong-Wan, Shen, Haifa
Format: Online
Language:English
Published: Ivyspring International Publisher 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966054/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966054/

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