Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding

Recent genome-wide association studies have pointed to single-nucleotide polymorphisms (SNPs) in genes encoding the neuronal calcium channel CaV1.2 (CACNA1C; rs1006737) and the presynaptic active zone protein Piccolo (PCLO; rs2522833) as risk factors for affective disorders, particularly major depre...

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Bibliographic Details
Main Authors: Schott, B H, Assmann, A, Schmierer, P, Soch, J, Erk, S, Garbusow, M, Mohnke, S, Pöhland, L, Romanczuk-Seiferth, N, Barman, A, Wüstenberg, T, Haddad, L, Grimm, O, Witt, S, Richter, S, Klein, M, Schütze, H, Mühleisen, T W, Cichon, S, Rietschel, M, Noethen, M M, Tost, H, Gundelfinger, E D, Düzel, E, Heinz, A, Meyer-Lindenberg, A, Seidenbecher, C I, Walter, H
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966038/