Mesenchymal Stem Cells from Rats with Chronic Kidney Disease Exhibit Premature Senescence and Loss of Regenerative Potential

Mesenchymal stem cell (MSC) transplantation has the potential for organ repair. Nevertheless, some factors might lessen the regenerative potential of MSCs, e.g. donor age or systemic disease. It is thus important to carefully assess the patient's suitability for autologous MSC transplantation....

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Bibliographic Details
Main Authors: Klinkhammer, Barbara Mara, Kramann, Rafael, Mallau, Monika, Makowska, Anna, van Roeyen, Claudia Renate, Rong, Song, Buecher, Eva Bettina, Boor, Peter, Kovacova, Katarina, Zok, Stephanie, Denecke, Bernd, Stuettgen, Esther, Otten, Simon, Floege, Juergen, Kunter, Uta
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965415/