Intrinsically Active and Pacemaker Neurons in Pluripotent Stem Cell-Derived Neuronal Populations

Neurons generated from pluripotent stem cells (PSCs) self-organize into functional neuronal assemblies in vitro, generating synchronous network activities. Intriguingly, PSC-derived neuronal assemblies develop spontaneous activities that are independent of external stimulation, suggesting the presen...

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Bibliographic Details
Main Authors: Illes, Sebastian, Jakab, Martin, Beyer, Felix, Gelfert, Renate, Couillard-Despres, Sébastien, Schnitzler, Alfons, Ritter, Markus, Aigner, Ludwig
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964285/