Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

The causative agent of tuberculosis (TB), Mycobacterium tuberculosis, remains an important worldwide health threat. Although TB is one of the oldest infectious diseases of man, a detailed understanding of the mycobacterial mechanisms underlying pathogenesis remains elusive. Here, we studied the role...

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Bibliographic Details
Main Authors: Stoop, Esther J M, Mishra, Arun K, Driessen, Nicole N, van Stempvoort, Gunny, Bouchier, Pascale, Verboom, Theo, van Leeuwen, Lisanne M, Sparrius, Marion, Raadsen, Susanne A, van Zon, Maaike, van der Wel, Nicole N, Besra, Gurdyal S, Geurtsen, Jeroen, Bitter, Wilbert, Appelmelk, Ben J, van der Sar, Astrid M
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963455/