Twist2 contributes to cisplatin-resistance of ovarian cancer through the AKT/GSK-3β signaling pathway
Cisplatin is regularly used in the treatment of ovarian cancer. However, the drug only provides a modest survival advantage, primarily due to chemoresistance and the upregulation of antiapoptotic machineries in ovarian cancer cells. Therefore, targeting the mechanisms responsible for cisplatin resis...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961411/ |