Tea polyphenols induced apoptosis of breast cancer cells by suppressing the expression of Survivin

To study the mechanism of tea polyphenols (TP)-induced apoptosis of breast cancer cells. Proliferation of MCF-7 and SK-BR-3 cells was evaluated by MTT assays. Cellular ultrastructure was examined by electron microscopy. Apoptosis was detected by TUNEL. PCNA、 Cyclin D1、 Cyclin E and Survivin expressi...

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Bibliographic Details
Main Authors: Chen, Xuesong, Li, Yu, Lin, Qiushi, Wang, Yan, Sun, Hong, Wang, Jian, Cui, Guoquan, Cai, Li, Dong, Xiaoqun
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960584/