Noncoding RNAs: Emerging Players in Muscular Dystrophies

The fascinating world of noncoding RNAs has recently come to light, thanks to the development of powerful sequencing technologies, revealing a variety of RNA molecules playing important regulatory functions in most, if not all, cellular processes. Many noncoding RNAs have been implicated in regulato...

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Main Authors:	Falcone, Germana, Perfetti, Alessandra, Cardinali, Beatrice, Martelli, Fabio
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960514/

id	pubmed-3960514
recordtype	oai_dc
spelling	pubmed-39605142014-04-13 Noncoding RNAs: Emerging Players in Muscular Dystrophies Falcone, Germana Perfetti, Alessandra Cardinali, Beatrice Martelli, Fabio Review Article The fascinating world of noncoding RNAs has recently come to light, thanks to the development of powerful sequencing technologies, revealing a variety of RNA molecules playing important regulatory functions in most, if not all, cellular processes. Many noncoding RNAs have been implicated in regulatory networks that are determinant for skeletal muscle differentiation and disease. In this review, we outline the noncoding RNAs involved in physiological mechanisms of myogenesis and those that appear dysregulated in muscle dystrophies, also discussing their potential use as disease biomarkers and therapeutic targets. Hindawi Publishing Corporation 2014 2014-03-04 /pmc/articles/PMC3960514/ /pubmed/24729974 http://dx.doi.org/10.1155/2014/503634 Text en Copyright © 2014 Germana Falcone et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Falcone, Germana Perfetti, Alessandra Cardinali, Beatrice Martelli, Fabio
spellingShingle	Falcone, Germana Perfetti, Alessandra Cardinali, Beatrice Martelli, Fabio Noncoding RNAs: Emerging Players in Muscular Dystrophies
author_facet	Falcone, Germana Perfetti, Alessandra Cardinali, Beatrice Martelli, Fabio
author_sort	Falcone, Germana
title	Noncoding RNAs: Emerging Players in Muscular Dystrophies
title_short	Noncoding RNAs: Emerging Players in Muscular Dystrophies
title_full	Noncoding RNAs: Emerging Players in Muscular Dystrophies
title_fullStr	Noncoding RNAs: Emerging Players in Muscular Dystrophies
title_full_unstemmed	Noncoding RNAs: Emerging Players in Muscular Dystrophies
title_sort	noncoding rnas: emerging players in muscular dystrophies
description	The fascinating world of noncoding RNAs has recently come to light, thanks to the development of powerful sequencing technologies, revealing a variety of RNA molecules playing important regulatory functions in most, if not all, cellular processes. Many noncoding RNAs have been implicated in regulatory networks that are determinant for skeletal muscle differentiation and disease. In this review, we outline the noncoding RNAs involved in physiological mechanisms of myogenesis and those that appear dysregulated in muscle dystrophies, also discussing their potential use as disease biomarkers and therapeutic targets.
publisher	Hindawi Publishing Corporation
publishDate	2014
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960514/
_version_	1612069681202462720

Noncoding RNAs: Emerging Players in Muscular Dystrophies

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