Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms

Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms

Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with intravenous drug self-administration procedure to...

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Bibliographic Details
Main Authors: Amchova, Petra, Kucerova, Jana, Giugliano, Valentina, Babinska, Zuzana, Zanda, Mary T., Scherma, Maria, Dusek, Ladislav, Fadda, Paola, Micale, Vincenzo, Sulcova, Alexandra, Fratta, Walter, Fattore, Liana
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960502/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960502/

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