Chemotherapeutic targeting of myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs), which expand in cancer-bearing hosts, contribute to the escape of malignant cells from immune destruction and impair the efficacy of immunotherapeutic interventions. We have recently demonstrated that the conventional chemotherapeutic agent doxorubicin selec...

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Bibliographic Details
Main Authors: Alizadeh, Darya, Katsanis, Emmanuel, Larmonier, Nicolas
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960296/